The Cocaine(COC) Drug Urine Test is a simple one step immunochromatographic assay for the rapid, qualitative detection of COC and primarily benzoylecgonine as metabolites in urine. The cutoff of the test is 300 ng/ml of COC. It is the same as the SAMHSA recommended assay cutoff.

The COC cocaine test provides only a preliminary analytical result. A more specific alternative chemical method must be used in order to obtain a confirmed analytical result. Gas chromatography, mass spectrometry (GC/MS) is the preferred method. Clinical consideration and professional judgment should be applied to any drug of abuse test result, particularly when preliminary positive results are used.

EXPLANATION OF THE TEST

Cocaine, derived from the leaves of the coca plant, is a potent central nervous system stimulant and a local anesthetic. Cocaine induces euphoria, confidence and a sense of increased energy in the user; these psychological effects are accompanied by increased heart rate, dilation of the pupils, fever, tremors and sweating. Cocaine is used by smoking, intravenous, intranasal or oral administration, and excreted in the urine primarily as benzoylecgonine in a short time. Benzoylecgonine has a longer biological half-life (5-8 hours) than cocaine (0.5-1.5 hours) and can generally be detected for 24-80 hours after cocaine use or exposure.

The COC cocaine test is based on the principle of the highly specific immunochemical reactions between antigens and antibodies, which are used for the analysis of specific substances in biological fluids. The sensitivity of the test is 300 ng/ml of COC.